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Skin Conditions

Clinical Trials for Patients With Dermatological Conditions

Psoriasis

Psoriasis is a chronic inflammatory skin condition associated with red thick scaling. It can occur in children and adults. When mild, psoriasis can be treated with topical steroids. When more severe various oral and injectable medications are available. Multiple new treatments are in clinical trials. Psoriasis is often associated with psoriatic arthritis, metabolic syndrome, diabetes and cardiovascular disease. The severity of psoriasis is associated with body mass, tobacco exposure and drinking alcohol. For more information: https://www.dermnetnz.org/topics/psoriasis ; https://www.aad.org/public/diseases/scaly-skin/psoriasis; https://www.psoriasis.org/

Atopic Dermatitis/Eczema

Atopic Dermatitis, often is referred to as eczema. Eczema refers to multiple different inflammatory rashes. Atopic Dermatitis is a chronic relapsing itchy variant of eczema seen in patients who have, or have family members with “atopy”. Atopy often includes other allergy based disorders seen in the patient and/or relatives: asthma, hay fever, and conjunctivitis, sensitivity to foods, wool as well as other skin and systemic findings. For more information: https://www.dermnetnz.org/topics/atopic-dermatitis ; https://www.aad.org/public/diseases/eczema/atopic-dermatitis ; https://nationaleczema.org/

Common Warts

Warts are a viral infection caused by exposure to the human papilloma virus (HPV). Over 170 subtypes of HPV have been identified. HPV types 1, 2, 4, and 7 are associated with common warts. Wart infections spread from one person to another through skin contact (No frogs nor toads are involved). Common warts often resolve without treatment within months once the body’s immunity recognised and destroys the virus. In many patients this immunity fails to develop and warts and persist for months to years. Treatments include destruction of the skin infected through cryosurgery (liquid nitrogen), podophyllotoxin; lasers; or electrosurgery; imiquimod is a topical agent used to enhance the immune response to the virus. New treatment are under development of those patient who despite these options fail to respond or cannot tolerate these treatments. https://www.dermnetnz.org/topics/sexually-acquired-human-papillomavirus; https://www.aad.org/public/diseases/contagious-skin-diseases/warts

Acne / Acne Scarring

Acne, or acne vulgaris (common) is an inflammatory process with affects tiny hair follicles on the face, chest, back and shoulders affecting over 90 % of teenagers. It is associated with papules (red bumps), pustules, open comedones (black heads) and closed comedones (tiny white firm papules). Acne usually resolves during the mid-twenties. In some individuals acne may persist into senior years. Factors proposed to be associated with the severity of and persistence of acne include: tobacco, sun, diets high in cholesterol, use of skin and hair products that promote acne (comedogenic products) and abrasive skin care. Treatment response varies among acne patients; new treatments are under development for those who fail to respond to current treatment. Many patients with acne can develop scarring. This may be associated with trauma to the lesions; but equally occurs spontaneously from the acne process on its own. Treatments for acne scarring are under development. https://www.dermnetnz.org/topics/acne ; https://www.aad.org/public/diseases/acne-and-rosacea/acne ; https://www.aad.org/public/diseases/acne-and-rosacea/acne-scars#treatment; https://acneandrosacea.org/